Selected article for: "causative agent and dependent RNA polymerase"

Author: Ansori, A. N. M.
Title: Discovery of therapeutic targets and potential drugs to fight severe acute respiratory syndrome coronavirus 2 (Sars-cov-2): A review
  • Cord-id: 3f6ojk3s
  • Document date: 2021_1_1
  • ID: 3f6ojk3s
    Snippet: SARS-CoV-2, the causative agent of COVID-19, has led to more than two million deaths worldwide. There are currently no specific therapies approved to treat COVID-19 and drug repositioning, rather than new drug discovery, which may be the best short-term option for controlling the pandemic. In this review, the author discusses important viral targets such as the papain-like protease, RNA-dependent RNA polymerase, 3-chymotrypsin-like protease, and spike protein. The information about chemical comp
    Document: SARS-CoV-2, the causative agent of COVID-19, has led to more than two million deaths worldwide. There are currently no specific therapies approved to treat COVID-19 and drug repositioning, rather than new drug discovery, which may be the best short-term option for controlling the pandemic. In this review, the author discusses important viral targets such as the papain-like protease, RNA-dependent RNA polymerase, 3-chymotrypsin-like protease, and spike protein. The information about chemical compounds and targets provided in this review will aid further in vitro and in vivo studies to discover drugs to treat COVID-19.

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