Author: Jing Qi; Yang Zhou; Jiao Hua; Liying Zhang; Jialin Bian; Beibei Liu; Zicen Zhao; Shuilin Jin
Title: The scRNA-seq expression profiling of the receptor ACE2 and the cellular protease TMPRSS2 reveals human organs susceptible to COVID-19 infection Document date: 2020_4_18
ID: grvc7pnt_32
Snippet: The scRNA-seq data of the kidney, ureter, and prostate from the urinary system were utilized for the data analysis. The analysis results of the kidney scRNA-seq data show high ACE2 and TMPRSS2 expression levels in the nephron epithelial cells, epithelial cells, endothelial cells, and mesangial cells. Particularly, the ratios of TMPRSS2-expressed are 10· 7%, 9· 6%, 12· 8%, and 14· 5% respectively, and the ratios of ACE2expressed are 2· 7%, 2Â.....
Document: The scRNA-seq data of the kidney, ureter, and prostate from the urinary system were utilized for the data analysis. The analysis results of the kidney scRNA-seq data show high ACE2 and TMPRSS2 expression levels in the nephron epithelial cells, epithelial cells, endothelial cells, and mesangial cells. Particularly, the ratios of TMPRSS2-expressed are 10· 7%, 9· 6%, 12· 8%, and 14· 5% respectively, and the ratios of ACE2expressed are 2· 7%, 2· 7%, 2· 7%, and 3· 0% respectively (Supplementary File: Figure S34 , Table 7 ).
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