Author: Erik Procko
                    Title: The sequence of human ACE2 is suboptimal for binding the S spike protein of SARS coronavirus 2  Document date: 2020_3_17
                    ID: jalijjmg_16
                    
                    Snippet: However, engineered ACE2 receptors with mutations at the interface may present binding 163 epitopes that are sufficiently different from native ACE2 that virus escape mutants can 164 emerge, or they may be strain specific and lack breadth to bind S in future coronavirus 165 outbreaks. 166.....
                    
                    
                    
                     
                    
                    
                    
                    
                        
                            
                                Document: However, engineered ACE2 receptors with mutations at the interface may present binding 163 epitopes that are sufficiently different from native ACE2 that virus escape mutants can 164 emerge, or they may be strain specific and lack breadth to bind S in future coronavirus 165 outbreaks. 166
 
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