Author: Cegielski, J P; Msengi, A E; Miller, S E
Title: Enteric viruses associated with HIV infection in Tanzanian children with chronic diarrhea. Cord-id: 6ty61h6d Document date: 1994_1_1
ID: 6ty61h6d
Snippet: OBJECTIVE To determine whether specific viruses are associated with HIV infection in Tanzanian children with chronic diarrhea. DESIGN Cross-sectional survey. SETTING Major national teaching hospital in Dar es Salaam, Tanzania. PATIENTS Consecutively admitted, human immunodeficiency virus (HIV)-infected and HIV-uninfected children with chronic diarrhea, and controls without diarrhea, aged 15 months to 5 years. MAIN OUTCOME MEASURE Enteric viruses identified by electron microscopy (EM) of fecal sp
Document: OBJECTIVE To determine whether specific viruses are associated with HIV infection in Tanzanian children with chronic diarrhea. DESIGN Cross-sectional survey. SETTING Major national teaching hospital in Dar es Salaam, Tanzania. PATIENTS Consecutively admitted, human immunodeficiency virus (HIV)-infected and HIV-uninfected children with chronic diarrhea, and controls without diarrhea, aged 15 months to 5 years. MAIN OUTCOME MEASURE Enteric viruses identified by electron microscopy (EM) of fecal specimens. RESULTS Small round structured viruses (SRSV) were more frequent in HIV-infected than HIV-uninfected children with chronic diarrhea (4 of 21 vs 1 of 32, prevalence ratio = 6.09, 90% confidence limits 1.03, 36.14). Rotavirus and coronavirus-like particles (CVLP) were not associated with HIV infection. CONCLUSION SRSV may be associated with HIV infection in Tanzanian children with chronic diarrhea. Larger, confirmatory studies are needed.
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