Author: Prete, Marcella; Favoino, Elvira; Catacchio, Giacomo; Racanelli, Vito; Perosa, Federico
Title: SARS-CoV-2 Inflammatory Syndrome. Clinical Features and Rationale for Immunological Treatment Cord-id: bvvpexje Document date: 2020_5_10
ID: bvvpexje
Snippet: The current pandemic coronavirus, SARS-CoV-2, is a global health emergency because of its highly contagious nature, the great number of patients requiring intensive care therapy, and the high fatality rate. In the absence of specific antiviral drugs, passive prophylaxis, or a vaccine, the treatment aim in these patients is to prevent the potent virus-induced inflammatory stimuli from leading to the acute respiratory distress syndrome (ARDS), which has a severe prognosis. Here, the mechanism of a
Document: The current pandemic coronavirus, SARS-CoV-2, is a global health emergency because of its highly contagious nature, the great number of patients requiring intensive care therapy, and the high fatality rate. In the absence of specific antiviral drugs, passive prophylaxis, or a vaccine, the treatment aim in these patients is to prevent the potent virus-induced inflammatory stimuli from leading to the acute respiratory distress syndrome (ARDS), which has a severe prognosis. Here, the mechanism of action and the rationale for employing immunological strategies, which range from traditional chemically synthesized drugs, anti-cytokine antibodies, human immunoglobulin for intravenous use, to vaccines, are reviewed.
Search related documents:
Co phrase search for related documents- acute respiratory syndrome and adaptive natural immunity: 1, 2
- acute respiratory syndrome and adaptor protein: 1, 2, 3, 4, 5
- acute respiratory syndrome and adenocarcinoma lung lobectomy: 1
- acute respiratory syndrome and adhanom ghebreyesus: 1, 2
- acute respiratory syndrome and long term persistence: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
- acute respiratory syndrome and lopinavir ritonavir: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73
- acute respiratory syndrome and low budget: 1, 2
- acute respiratory syndrome and lung lobectomy: 1, 2
- acute respiratory syndrome and lymphocyte rna: 1, 2, 3, 4, 5
- acute respiratory syndrome and mab humanize monoclonal antibody: 1
- acute respiratory syndrome and mabs specific: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21
- acute respiratory syndrome and macrophage activation: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72
- acute respiratory syndrome and macrophage activation syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62
- acute respiratory syndrome and macrophage expression: 1, 2, 3, 4, 5, 6, 7, 8, 9
- lopinavir ritonavir and macrophage activation: 1, 2, 3
- lopinavir ritonavir and macrophage activation syndrome: 1, 2, 3
Co phrase search for related documents, hyperlinks ordered by date