Selected article for: "analog scale and study design"

Author: Bush, Carrie M; Prosser, John D; Morrison, Michele P; Sandhu, Guri; Wenger, Karl H; Pashley, David H; Birchall, Martin A; Postma, Gregory N; Weinberger, Paul M
Title: New technology applications: Knotless barbed suture for tracheal resection anastomosis.
  • Cord-id: 3l3k020v
  • Document date: 2012_1_1
  • ID: 3l3k020v
    Snippet: OBJECTIVES/HYPOTHESIS Tracheal resection anastomoses are often under tension and can be technically challenging. New suture materials such as V-loc (barbed, knotless wound closure device) may offer advantages over conventional methods. The objective of this study is to determine if a running V-loc suture is of comparable tensile strength to conventional closure. STUDY DESIGN Laboratory based study of human cadaveric tissue. METHODS Fresh human cadaveric tracheas were dissected and incised into s
    Document: OBJECTIVES/HYPOTHESIS Tracheal resection anastomoses are often under tension and can be technically challenging. New suture materials such as V-loc (barbed, knotless wound closure device) may offer advantages over conventional methods. The objective of this study is to determine if a running V-loc suture is of comparable tensile strength to conventional closure. STUDY DESIGN Laboratory based study of human cadaveric tissue. METHODS Fresh human cadaveric tracheas were dissected and incised into segments. Anastomosis of adjacent segments was then performed with either submucosal interrupted 3-0 Vicryl, or a running submucosal 3-0 V-loc suture. Anastomosed specimens were stretched to failure on an Instron force tension machine. Surgeon satisfaction was recorded by visual analog scale (VAS). RESULTS The tensile strength of 12 tracheal anastomoses was tested. Video documentation of V-loc suture technique and anastomosis failure was recorded. In both Vicryl (80%) and V-loc (100%) anastomoses, failure occurred at the membranous intercartilaginous region. In 20% of the Vicryl anastomoses, the suture was noted to break prior to tissue failure. Anastomoses with V-loc suture had equivalent failure force (mean, 59 N) compared to interrupted Vicryl (51 N), with P = .57. On VAS, surgeons were more satisfied with V-loc suture closure compared to interrupted Vicryl closure (paired t test, P = .003). CONCLUSIONS Tracheal anastomosis with running v-loc suture is a feasible alternative to conventional closure with interrupted Vicryl suture. V-loc suture provided a surgical advantage by improved ease of use.

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