Selected article for: "discontinuous RNA synthesis and leader trs"

Author: Hazel Stewart; Katherine Brown; Adam M. Dinan; Nerea Irigoyen; Eric J. Snijder; Andrew E. Firth
Title: The transcriptional and translational landscape of equine torovirus
  • Document date: 2018_4_7
  • ID: mozfm5ds_49
    Snippet: Bafinivirus replication produces three sgRNAs which share an identical 42-nt leader 424 also found at the far 5' terminus of the genome, indicating this species utilises 425 discontinuous RNA synthesis in a manner similar to the corona-and arteriviruses 426 (35). However there was preliminary evidence that two of the three sgRNAs exhibit 427 diversity in their junction sites, suggesting the anti-TRS may bind to multiple sites 428 within the 5' le.....
    Document: Bafinivirus replication produces three sgRNAs which share an identical 42-nt leader 424 also found at the far 5' terminus of the genome, indicating this species utilises 425 discontinuous RNA synthesis in a manner similar to the corona-and arteriviruses 426 (35). However there was preliminary evidence that two of the three sgRNAs exhibit 427 diversity in their junction sites, suggesting the anti-TRS may bind to multiple sites 428 within the 5' leader during strand transfer, consistent with our suggestion that whilst 429 a threshold level of homology is required this is not limited to particular primary 430

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