Selected article for: "multiple sequence alignment and sequence conservation"

Author: MJ Morwitzer; A Corona; L Zinzula; E Fanunza; C Nigri; S Distinto; C Vornholt; V Kumar; E Tramontano; SP Reid
Title: Mutation of Ebola virus VP35 Ser129 uncouples interferon antagonist and replication functions
  • Document date: 2019_8_7
  • ID: cbyzdnrp_41
    Snippet: Moreover, multiple sequence alignment of all ebolavirus species revealed conservation among 366 all ebolavirus species except BOMV ( Figure 1B ). BOMV is a newly identified ebolavirus species 367 and has not yet been shown to be pathogenic in humans. All other ebolaviruses except RESTV 368 are pathogenic in humans, thus we reasoned the conservation of Ser129 may be functionally 369.....
    Document: Moreover, multiple sequence alignment of all ebolavirus species revealed conservation among 366 all ebolavirus species except BOMV ( Figure 1B ). BOMV is a newly identified ebolavirus species 367 and has not yet been shown to be pathogenic in humans. All other ebolaviruses except RESTV 368 are pathogenic in humans, thus we reasoned the conservation of Ser129 may be functionally 369

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