Obesity: A potential risk factor for infection and mortality in the current COVID-19 epidemic

Jayawardena, Ranil; Jeyakumar, Dhanushya T.; Misra, Anoop; Hills, Andrew P.; Ranasinghe, Priyanga

BACKGROUND AND AIMS: COVID-19 is an ongoing global pandemic, affecting nearly 35 million people from 214 countries as at September 30, 2020. Emerging evidence suggests that obesity is a potential risk factor for communicable diseases, including viral infections. Therefore, we investigated the relationship between obesity prevalence of the total adult population and COVID-19 infection and mortality rates, in different countries. METHODS: A total of 54 countries from six continents were selected. Country-specific obesity prevalence data were retrieved from the latest non-communicable diseases profiles released by the Non-communicable Diseases and Mental Health Cluster of World Health Organization, while the real time statistics from the Worldometer website were used to extract data on COVID-19 infections and mortality per million of the total population as of September 30, 2020. RESULTS: Obesity prevalence data ranged from 2.0% (Vietnam) to 35.0% (Saudi Arabia). Among the selected countries, the highest number of COVID-19 cases per million was documented in Qatar (n = 44,789) while the lowest was reported from Vietnam (n = 11). Highest mortality per million population due to COVID-19 infections occurred in Peru (n = 981), in contrast with the smallest number reported in Mongolia (n = 0). A significant positive correlation (r = 0.46; p < 0.001) was observed between the total number of COVID-19 infections and the prevalence of obesity. COVID-19 mortality was also significantly correlated (r = 0.34; p < 0.05) with the prevalence of obesity. CONCLUSIONS: Obesity prevalence in each country was significantly associated with both infection and mortality rate of COVID-19.