Author: Xavier Hernandez-Alias; Martin Schaefer; Luis Serrano
Title: Translational adaptation of human viruses to the tissues they infect Document date: 2020_4_7
ID: 0rk2dw4e_7
Snippet: Publicly available genomic data comprised a total of 564 human-infecting viruses, distributed among 33 families and covering all seven Baltimore categories (Sup. Table 1 ). Across this diversity, six main viral tropisms were defined for 182 viruses based on the ViralZone curated database 25 : neurons, immune cells, respiratory tract, hepatocytes, intestine, and epithelial cells (Fig. 1A) . Their corresponding coding sequences constituted a total .....
Document: Publicly available genomic data comprised a total of 564 human-infecting viruses, distributed among 33 families and covering all seven Baltimore categories (Sup. Table 1 ). Across this diversity, six main viral tropisms were defined for 182 viruses based on the ViralZone curated database 25 : neurons, immune cells, respiratory tract, hepatocytes, intestine, and epithelial cells (Fig. 1A) . Their corresponding coding sequences constituted a total of 4935 viral proteins (Sup. Table 1 ), for which we determined the Relative Codon Usage (RCU, i.e. the contribution of each synonymous codon to the amino acid it encodes, see Methods).
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