Author: Zhichao Feng; Jennifer Li; Shanhu Yao; Qizhi Yu; Wenming Zhou; Xiaowen Mao; Huiling Li; Wendi Kang; Xin Ouyang; Ji Mei; Qiuhua Zeng; Jincai Liu; Xiaoqian Ma; Pengfei Rong; Wei Wang
Title: The Use of Adjuvant Therapy in Preventing Progression to Severe Pneumonia in Patients with Coronavirus Disease 2019: A Multicenter Data Analysis Document date: 2020_4_10
ID: k65501xp_5
Snippet: The world has witnessed the rapid escalation of 2019 coronavirus disease , caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), now becoming a global pandemic. 1 While many patients may be asymptomatic or experience only mild symptoms, reports so far have identified the elderly and patients with chronic comorbidities such as hypertension, diabetes, and cardiovascular disease to be at higher risk of progression to severe COVID-1.....
Document: The world has witnessed the rapid escalation of 2019 coronavirus disease , caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), now becoming a global pandemic. 1 While many patients may be asymptomatic or experience only mild symptoms, reports so far have identified the elderly and patients with chronic comorbidities such as hypertension, diabetes, and cardiovascular disease to be at higher risk of progression to severe COVID-19 pneumonia, characterized by acute respiratory distress syndrome (ARDS) and/or multiorgan failure. [2] [3] [4] These severe patients require more intensive medical resource utilization and have worse prognosis, with a case fatality rate about 20 times higher than that of non-severe patients. 5, 6 While the implementation of effective prevention measures is essential, there clearly exists an urgent need for interventions to modulate disease progression in the face of an increasing number of infected individuals, which have overwhelmed the capacity of hospital systems in some countries.
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