Author: Daniel Bean; Zeljko Kraljevic; Thomas Searle; Rebecca Bendayan; Andrew Pickles; Amos Folarin; Lukasz Roguski; Kawsar Noor; Anthony Shek; Kevin o'gallagher; Rosita Zakeri; Ajay Shah; James Teo; Richard JB Dobson
Title: Treatment with ACE-inhibitors is associated with less severe disease with SARS-Covid-19 infection in a multi-site UK acute Hospital Trust Document date: 2020_4_11
ID: 60wcvkbn_12
Snippet: Findings from unadjusted logistic regression models indicated that individuals on ACEi had lower likelihood of severe disease (OR 0·42 (CI 0·14-1·00), p=0·058). These associations were only partially attenuated when adjustments for gender and age were included (Model 1 in Table 2 ). Furthermore, these associations remained significant and were only partially attenuated when the model was additionally adjusted for hypertension (Model 2 in Tabl.....
Document: Findings from unadjusted logistic regression models indicated that individuals on ACEi had lower likelihood of severe disease (OR 0·42 (CI 0·14-1·00), p=0·058). These associations were only partially attenuated when adjustments for gender and age were included (Model 1 in Table 2 ). Furthermore, these associations remained significant and were only partially attenuated when the model was additionally adjusted for hypertension (Model 2 in Table 2 ) and further for other comorbidities diabetes and ischaemic heart disease or heart failure (Model 3 in Table 2 ). Odds ratios and p-values for all variables in each model are shown in Supplementary Table 1. Males were found to have a higher likelihood of severe disease in Model 3 (OR 2.00 (CI 1.00-4.00), p=0.037).
Search related documents:
Co phrase search for related documents- age gender and CI male: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- age gender and CI severe disease: 1, 2, 3, 4, 5, 6
- age gender and heart failure: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- age gender and heart failure ischaemic heart disease: 1
- age gender and high likelihood: 1, 2, 3
- age gender and ischaemic heart: 1, 2, 3, 4, 5, 6
- age gender and ischaemic heart disease: 1, 2, 3, 4, 5, 6
- age gender and logistic regression model: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- age gender and low likelihood: 1, 2, 3, 4
- age gender and model variable: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- age gender and odd ratio: 1, 2, 3, 4, 5, 6, 7, 8, 9
- CI male and CI severe disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
- CI male and heart failure: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
- CI male and ischaemic heart: 1
- CI male and ischaemic heart disease: 1
- CI male and logistic regression model: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
- CI male and model variable: 1
- CI male and odd ratio: 1, 2, 3
- CI severe disease and heart failure: 1, 2, 3, 4, 5
Co phrase search for related documents, hyperlinks ordered by date