Mutations, Recombination and Insertion in the Evolution of 2019-nCoV

Aiping Wu; Peihua Niu; Lulan Wang; Hangyu Zhou; Xiang Zhao; Wenling Wang; Jingfeng Wang; Chengyang Ji; Xiao Ding; Xianyue Wang; Roujian Lu; Sarah Gold; Saba Aliyari; Shilei Zhang; Ellee Vikram; Angela Zou; Emily Lenh; Janet Chen; Fei Ye; Na Han; Yousong Peng; Haitao Guo; Guizhen Wu; Taijiao Jiang; Wenjie Tan; Genhong Cheng

The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.02.29.971101 doi: bioRxiv preprint genomes to avoid random mutations or sequencing errors that might mislead the inference. Second, genomes in G1 and G2 were grouped by the number of varied nucleotides compared with the reference sequence of G1 (EPI_ISL_402125) or G2 (EPI_ISL_406801). In total, we divided all the genomes in G1 and G2 separately into three groups with 1, 2 and 3 varied nucleotides. Third, the strains in groups with 1 varied 5 nucleotides were plotted in the tree with branch length of 1, then, strains with 2 varied nucleotides were plotted in the tree with branch length of 2, it should be noted that the strains with substitution site contained the site in group 1 was plotted behind the branch with responding site. Similar ways were used to group 3.