Advance of Novel Coronavirus Registration Clinical Trial

gao song; meng qun cheng; xian wen wei

As shown in Table 1 , 67.67% of the studies were intervention studies and 25.00% were observational studies. 28.02% of the studies were treated with CMT, 12.93% were treated with BI, 28.02% were treated with TCM, and 8.62% were treated with BEI.The early stage accounted for 41.81% of all studies, and 20.69% of the studies were late stages. 53.88% of research is mainly funded by the public, and 57.76% of research is being recruited. However, 22.84% of the studies did not receive ethical approval, and 47.41% were not confirmed by the data management committee. Table 2 , only 6.47% of the studies were multicenter studies. 44.83% of the study participants were between 100 to 300, and only 3.45% of the studies were >1000. 43.53% of the studies were completed within 4-12 months, and only 2.16% were completed within 1 month. 75.0% of the studies used random assignments, but 70.69% of the studies lacked information on blinding. Table 3 ,the chisquare tests revealed significant differences in the design characteristics, depending on the Type of Study, for the items of participants number(P=0.000), study duration (P=0.008), study assignment (P=0.000) and blind method (P=0.000). The number of participants in 45.86% interventional and 43.10% observational studies was concentrated in the 100-300 range.46.50% interventional and 37.93% observational studies were completed within 4-12 months. 78.98% of the interventional All rights reserved. No reuse allowed without permission. author/funder, who has granted medRxiv a license to display the preprint in perpetuity.