Selected article for: "category directly IFITMs associate and interferon action"
Author: Xiaoyang Ji; Chunming Zhang; Yubo Zhai; Zhonghai Zhang; Yiqing Xue; Chunli Zhang; Guangming Tan; Gang Niu
Title: TWIRLS, an automated topic-wise inference method based on massive literature, suggests a possible mechanism via ACE2 for the pathological changes in the human host after coronavirus infection
  • Document date: 2020_2_26
    • ID: f21dknmb_19
    Snippet: The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.02. 24.20025437 doi: medRxiv preprint studies (average 0.03% in the control test of random samplings, p <1.5676e-61). The IFITMs family plays crucial roles in the induction of interferons during viral infections. Under the action of interferon, IFITMs disrupts intracellular cholesterol homeostasis and prevents the virus from entering the host ce.....
    Document: The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.02. 24.20025437 doi: medRxiv preprint studies (average 0.03% in the control test of random samplings, p <1.5676e-61). The IFITMs family plays crucial roles in the induction of interferons during viral infections. Under the action of interferon, IFITMs disrupts intracellular cholesterol homeostasis and prevents the virus from entering the host cell [11] . However, TWIRLS did not directly associate IFITMs with any category, so we needed to provide more information so that TWIRLS can determine which part of these genes might be involved in the coronavirus infection and host body response.

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