Selected article for: "clinical treatment and high affinity"
Author: Xiaoyang Ji; Chunming Zhang; Yubo Zhai; Zhonghai Zhang; Yiqing Xue; Chunli Zhang; Guangming Tan; Gang Niu
Title: TWIRLS, an automated topic-wise inference method based on massive literature, suggests a possible mechanism via ACE2 for the pathological changes in the human host after coronavirus infection
  • Document date: 2020_2_26
    • ID: f21dknmb_2
    Snippet: Researchers have found that the new SARS-CoV-2 and SARS coronaviruses invade human cells in target tissues in a similar manner via high-affinity binding to angiotensin-converting enzyme 2 (ACE2) [1] . In recent epidemiological investigations of the spread of the SARS-CoV-2 and a preliminary study of the clinical characteristics of this disease [2] [3] [4] [5] [6] , researchers have found that patients infected with the new coronavirus have severe.....
    Document: Researchers have found that the new SARS-CoV-2 and SARS coronaviruses invade human cells in target tissues in a similar manner via high-affinity binding to angiotensin-converting enzyme 2 (ACE2) [1] . In recent epidemiological investigations of the spread of the SARS-CoV-2 and a preliminary study of the clinical characteristics of this disease [2] [3] [4] [5] [6] , researchers have found that patients infected with the new coronavirus have severe symptoms similar to those of the SARS infection. The first batch of clinical data reports of SARS-CoV-2 infection cases in China revealed "cytokine storms" in critically ill patients [7, 8] . However, the mechanism of the viral infection and pathological changes in the immune system is still lacking. The sooner this information is added to the current clinical knowledge of these viruses, the better the control and treatment of this disease.

    Search related documents:
    Co phrase search for related documents
    • clinical characteristic and critically ill patient: 1
    • clinical characteristic and cytokine storm: 1
    • clinical characteristic and disease clinical characteristic: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
    • clinical characteristic and human cell: 1, 2
    • clinical characteristic and immune system: 1
    • clinical knowledge and critically ill patient: 1, 2, 3
    • clinical knowledge and cytokine storm: 1, 2, 3, 4, 5, 6, 7
    • clinical knowledge and epidemiological investigation: 1
    • clinical knowledge and high affinity: 1
    • clinical knowledge and high affinity binding: 1
    • clinical knowledge and human cell: 1, 2, 3
    • clinical knowledge and immune system: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16
    • critically ill patient and cytokine storm: 1, 2, 3, 4, 5, 6, 7, 8
    • critically ill patient and human cell: 1
    • critically ill patient and immune system: 1
    • cytokine storm and disease clinical characteristic: 1
    • cytokine storm and high affinity: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • cytokine storm and high affinity binding: 1, 2, 3, 4
    • cytokine storm and human cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25