Author: Zhichao Feng; Jennifer Li; Shanhu Yao; Qizhi Yu; Wenming Zhou; Xiaowen Mao; Huiling Li; Wendi Kang; Xin Ouyang; Ji Mei; Qiuhua Zeng; Jincai Liu; Xiaoqian Ma; Pengfei Rong; Wei Wang
Title: The Use of Adjuvant Therapy in Preventing Progression to Severe Pneumonia in Patients with Coronavirus Disease 2019: A Multicenter Data Analysis Document date: 2020_4_10
ID: k65501xp_47
Snippet: There were several limitations in this study. First, our study was conducted by retrospective data analysis. Second, some cases had incomplete laboratory test results, given the variation in the clinical management among different hospitals. All data generation was clinically driven and not systematic. Third, because most patients had recovered and discharged at the time of data cutoff and only 2 patients died during admission, the impact of adju.....
Document: There were several limitations in this study. First, our study was conducted by retrospective data analysis. Second, some cases had incomplete laboratory test results, given the variation in the clinical management among different hospitals. All data generation was clinically driven and not systematic. Third, because most patients had recovered and discharged at the time of data cutoff and only 2 patients died during admission, the impact of adjuvant treatment on the clinical outcomes cannot be analyzed. Forth, there were limited hypertensive patients who received ACEI or ARB therapy, so we cannot analyze the effect of AECI and ARB respectively. A larger cohort study of COVID-19 patients with hypertension from other cities in China and other countries would help to further validate the potential protective effect of AECI/ARB therapy.
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