Selected article for: "clinical evidence and study design"

Author: Daniel Bean; Zeljko Kraljevic; Thomas Searle; Rebecca Bendayan; Andrew Pickles; Amos Folarin; Lukasz Roguski; Kawsar Noor; Anthony Shek; Kevin o'gallagher; Rosita Zakeri; Ajay Shah; James Teo; Richard JB Dobson
Title: Treatment with ACE-inhibitors is associated with less severe disease with SARS-Covid-19 infection in a multi-site UK acute Hospital Trust
  • Document date: 2020_4_11
  • ID: 60wcvkbn_10
    Snippet: Our total cohort consists of 205 confirmed positive symptomatic inpatients aged 63 + 20 (SD) years and 52% males (Table 1) . Baseline characteristics are 51·2% with hypertension, 30·2% with diabetes and 14·6% with ischaemic heart disease or heart failure. The percentage of patients that have a positive mention of a certain disorder in each of the two groups (Dead or Critical Care, Other) derived via the NLP for medical concept annotations with.....
    Document: Our total cohort consists of 205 confirmed positive symptomatic inpatients aged 63 + 20 (SD) years and 52% males (Table 1) . Baseline characteristics are 51·2% with hypertension, 30·2% with diabetes and 14·6% with ischaemic heart disease or heart failure. The percentage of patients that have a positive mention of a certain disorder in each of the two groups (Dead or Critical Care, Other) derived via the NLP for medical concept annotations with F1 > 80% and more than 10 annotated mentions are shown in Figure 1 (performance shown in Figure 2 ). All NLP-detected positive mentions of hypertension, diabetes, ischaemic heart disease or heart failure were manually reviewed at a patient level and false positive rates calculated 1·9%, 3·2%, 31%, 0% respectively.

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