Selected article for: "RdRp RNA dependent RNA polymerase and RNA polymerase"

Author: Shay Leary; Silvana Gaudieri; Abha Chopra; Suman Pakala; Eric Alves; Mina John; Suman Das; Simon Mallal; Phillips Jane Phillips
Title: Three adjacent nucleotide changes spanning two residues in SARS-CoV-2 nucleoprotein: possible homologous recombination from the transcription-regulating sequence
  • Document date: 2020_4_11
  • ID: 9xueqdri_14
    Snippet: Interestingly, the M175 polymorphism in the membrane glycoprotein appears to only be present on the KR-LGG combination (of the 132 sequences with this polymorphism 131 are from Europe and 1 from North America) (Supplementary Table 2 ). When the other common polymorphisms (>5%) observed in the NSP2, NSP6, RNA-dependent RNA polymerase (RdRP), membrane glycoprotein and helicase are taken into account, there are at present eight main circulating stra.....
    Document: Interestingly, the M175 polymorphism in the membrane glycoprotein appears to only be present on the KR-LGG combination (of the 132 sequences with this polymorphism 131 are from Europe and 1 from North America) (Supplementary Table 2 ). When the other common polymorphisms (>5%) observed in the NSP2, NSP6, RNA-dependent RNA polymerase (RdRP), membrane glycoprotein and helicase are taken into account, there are at present eight main circulating strains at >5% frequency in the database all within one to three amino acid polymorphism networks (Supplementary Table 2 ).

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