Author: Dietrich, M. L.; Norton, E. B.; Elliott, D.; Smira, A. R.; Rouelle, J. A.; Bond, N. G.; Aime-Marcelin, K.; Prystowsky, A.; Kemnitz, R.; Sarma, A.; Himmelfarb, S. T.; Sharma, N.; Stone, A. E.; Craver, R.; Lindrose, A. R.; Smitley, L. A.; Uddo, R. B.; Myers, L.; Drury, S. S.; Schieffelin, J. S.; Robinson, J. E.; Zwezdaryk, K. J.
Title: SARS-CoV-2 Seroprevalence Rates of Children in Louisiana During the State Stay at Home Order. Cord-id: 7eyttfre Document date: 2020_7_8
ID: 7eyttfre
Snippet: Children (less than 19 years) account for 20% of the US population but currently represent less than 2% of coronavirus disease 2019 (COVID-19) cases. Because infected children often have few or no symptoms and may not be tested, the extent of infection in children is poorly understood. METHODS During the March 18th-May 15th 2020 Louisiana Stay At Home Order, 1690 blood samples from 812 individuals from a Childrens Hospital were tested for antibodies to severe acute respiratory syndrome coronavir
Document: Children (less than 19 years) account for 20% of the US population but currently represent less than 2% of coronavirus disease 2019 (COVID-19) cases. Because infected children often have few or no symptoms and may not be tested, the extent of infection in children is poorly understood. METHODS During the March 18th-May 15th 2020 Louisiana Stay At Home Order, 1690 blood samples from 812 individuals from a Childrens Hospital were tested for antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein. Demographics, COVID-19 testing, and clinical presentation abstracted from medical records were compared with local COVID-19 cases. RESULTS In total, 62 subjects (7.6%) were found to be seropositive. The median age was 11 years with 50.4% female. The presenting complaint of seropositive patients was chronic illness (43.5%). Only 18.2% had a previous positive COVID-19 PCR or antibody test. Seropositivity was significantly associated with parish (counties), race, and residence in a low-income area. Importantly, seropositivity was linearly correlated with cumulative COVID-19 case number for all ages by parish. CONCLUSION In a large retrospective study, the seropositivity prevalence for SARS-CoV-2 in children in Louisiana during the mandated Stay At Home Order was 7.6%. Residence location, race, and lower socioeconomic factors were linked to more frequent seropositivity in children and correlated to regional COVID-19 case rates. Thus, a significant number of children in Louisiana had SARS-CoV-2 infections that went undetected and unreported and may have contributed to virus transmission.
Search related documents:
Co phrase search for related documents- absence presence and acute ards respiratory distress syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
- absence presence and acute infection: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23
- absence presence and additional factor: 1
- absence presence and liver failure: 1, 2
- absence presence and low household income: 1
- academic institution and acute infection: 1, 2, 3, 4, 5
- academic institution and local academic institution: 1
- acute ards respiratory distress syndrome and additional factor: 1, 2
- acute ards respiratory distress syndrome and liver failure: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- acute infection and additional factor: 1, 2, 3, 4, 5
- acute infection and liver failure: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute infection and low household income: 1
- additional factor and liver failure: 1, 2
Co phrase search for related documents, hyperlinks ordered by date