Selected article for: "effective population size and population size"
Author: Shu-Miaw Chaw; Jui-Hung Tai; Shi-Lun Chen; Chia-Hung Hsieh; Sui-Yuan Chang; Shiou-Hwei Yeh; Wei-Shiung Yang; Pei-Jer Chen; Hurng-Yi Wang
Title: The origin and underlying driving forces of the SARS-CoV-2 outbreak
  • Document date: 2020_4_14
    • ID: bawgldfi_20
    Snippet: Watterson's estimator of θ, and nucleotide diversity (π) of the SARS-CoV-2. Since both π 220 and θ are estimators of 4Nu (N and u are the effective population size and mutation rate, 221 respectively), they should be close to each other at the mutation-drift equilibrium [25] . The copyright holder for this preprint (which was not peer-reviewed) is . sequences from China exhibited higher genetic variation in terms of the number of 227 segregat.....
    Document: Watterson's estimator of θ, and nucleotide diversity (π) of the SARS-CoV-2. Since both π 220 and θ are estimators of 4Nu (N and u are the effective population size and mutation rate, 221 respectively), they should be close to each other at the mutation-drift equilibrium [25] . The copyright holder for this preprint (which was not peer-reviewed) is . sequences from China exhibited higher genetic variation in terms of the number of 227 segregating sites, θ and π, than the rest of the world combined, consistent with the 228 observation that the outbreak originated in China, as the source populations are expected to 229 exhibit higher genetic variation than derived populations [25] .

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