Author: Dorothea Bestle; Miriam Ruth Heindl; Hannah Limburg; Thuy Van Lam van; Oliver Pilgram; Hong Moulton; David A. Stein; Kornelia Hardes; Markus Eickmann; Olga Dolnik; Cornelius Rohde; Stephan Becker; Hans-Dieter Klenk; Wolfgang Garten; Torsten Steinmetzer; Eva Böttcher-Friebertshäuser
Title: TMPRSS2 and furin are both essential for proteolytic activation and spread of SARS-CoV-2 in human airway epithelial cells and provide promising drug targets Document date: 2020_4_15
ID: anedg12x_12
Snippet: CoV-2 S protein with a C-terminal Myc-6xHis-tag, and incubated in the absence and 174 presence of the potent synthetic furin inhibitor MI-1851 (cf. Fig. S1 ; manuscript in 175 preparation). At 24 h post transfection, cell lysates were subjected to SDS-PAGE and 176.....
Document: CoV-2 S protein with a C-terminal Myc-6xHis-tag, and incubated in the absence and 174 presence of the potent synthetic furin inhibitor MI-1851 (cf. Fig. S1 ; manuscript in 175 preparation). At 24 h post transfection, cell lysates were subjected to SDS-PAGE and 176
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