Author: Craig Thompson; Nicholas Grayson; Robert Paton; José Lourenço; Bridget Penman; Lian Ni Lee; Valerie Odon; Juthathip Mongkolsapaya; Senthil Chinnakannan; Wanwisa Dejnirattisai; Matthew Edmans; Alexander Fyfe; Carol Imlach; Kreepa Kooblall; Nicholas Lim; Chang Liu; Cesar Lopez-Camacho; Carol-Anne McInally; Narayan Ramamurthy; Jeremy Ratcliff; Piyada Supasa; Beibei Wang; Alexander J Mentzer; Marc Turner; Calum Semple; John Kenneth Baillie; Heli Harvala; Gavin Screaton; Nigel Temperton; Paul Klenerman; Lisa Jarvis; Sunetra Gupta; Peter Simmonds
Title: Neutralising antibodies to SARS coronavirus 2 in Scottish blood donors - a pilot study of the value of serology to determine population exposure Document date: 2020_4_17
ID: nm2bq717_14
Snippet: Larger values correspond to samples with stronger antibody responses which require higher dilutions to reduce neutralisation. The parameter describes the asymptote of the curve and was fixed to 100 (100% neutralisation was the maximum). The parameter " 175 describes the steepness of the slope for the sigmoidal curve and was restricted to take values < 0 (only negative responses of neutralisation to dose were permitted). The quality of the (Invern.....
Document: Larger values correspond to samples with stronger antibody responses which require higher dilutions to reduce neutralisation. The parameter describes the asymptote of the curve and was fixed to 100 (100% neutralisation was the maximum). The parameter " 175 describes the steepness of the slope for the sigmoidal curve and was restricted to take values < 0 (only negative responses of neutralisation to dose were permitted). The quality of the (Inverness Health Board) areas. There was an approximately equal representation of males and females amongst donors but a restricted age range from 18 (minimum donor age) to 75 ( Fig. 1) ; this was also skewed towards older age ranges compared to the Scottish population within that range ( Fig. S1 ; Suppl. Data).
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