Author: Xavier Hernandez-Alias; Martin Schaefer; Luis Serrano
Title: Translational adaptation of human viruses to the tissues they infect Document date: 2020_4_7
ID: 0rk2dw4e_22
Snippet: In short, we report that the new pandemic SARS-CoV-2 coronavirus has evolved to significantly increase its translational adaptation to the human tissues. While it might not be sufficient on its own, the coincidence of both translational efficiency and entry receptor expression supports an optimal tropism of the alveoli but also the upper respiratory tract (Fig. 3C ), which has recently been related to the higher transmissibility of the novel str.....
Document: In short, we report that the new pandemic SARS-CoV-2 coronavirus has evolved to significantly increase its translational adaptation to the human tissues. While it might not be sufficient on its own, the coincidence of both translational efficiency and entry receptor expression supports an optimal tropism of the alveoli but also the upper respiratory tract (Fig. 3C ), which has recently been related to the higher transmissibility of the novel strain 21 .
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