Author: Xavier Hernandez-Alias; Martin Schaefer; Luis Serrano
Title: Translational adaptation of human viruses to the tissues they infect Document date: 2020_4_7
ID: 0rk2dw4e_9
Snippet: Given the impact of viral tropism on the RCU, we sought to determine the main codon differences between the six defined target tissues. By using a linear discriminant analysis (see Methods), the 182 tropism-defined viruses were classified in six clear clusters, regardless of other factors such as the phylogenetic lineage (Fig. 1C) . In consequence, we observe that specific codon usage profiles are associated with the tissue tropism of human-infec.....
Document: Given the impact of viral tropism on the RCU, we sought to determine the main codon differences between the six defined target tissues. By using a linear discriminant analysis (see Methods), the 182 tropism-defined viruses were classified in six clear clusters, regardless of other factors such as the phylogenetic lineage (Fig. 1C) . In consequence, we observe that specific codon usage profiles are associated with the tissue tropism of human-infecting viruses.
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