Selected article for: "high sequence identity and homology model"
Author: Amrita Roy; Liangzhong Lim; Shagun Srivastava; Jianxing Song
Title: Unique properties of Zika NS2B-NS3pro complexes as decoded by experiments and MD simulations
  • Document date: 2016_9_28
    • ID: l82aakrk_24
    Snippet: longer Zika NS2B-NS3pro constructs prevented from further determination of its structure by crystallography or NMR. On the other hand, Zika and Dengue viruses have a high sequence identity for the NS2B (35.19%) and NS3pro (56.67%) respectively, which is sufficient to allow to build up a homology model (26, 27) . Therefore, with MODELLER software suite (9v10) (26), we generated a homology model of the Zika NS2B-NS3pro in the "open" form by use of .....
    Document: longer Zika NS2B-NS3pro constructs prevented from further determination of its structure by crystallography or NMR. On the other hand, Zika and Dengue viruses have a high sequence identity for the NS2B (35.19%) and NS3pro (56.67%) respectively, which is sufficient to allow to build up a homology model (26, 27) . Therefore, with MODELLER software suite (9v10) (26), we generated a homology model of the Zika NS2B-NS3pro in the "open" form by use of a Dengue crystal structure (PDB code: 2FOM) as a template. This Dengue crystal structure

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