The role of post-Golgi transport pathways and sorting motifs in the plasmodesmal targeting of the movement protein (MP) of Ourmia melon virus (OuMV)

Natali Ozber; Paolo Margaria; Charles T. Anderson; Massimo Turina; Cristina Rosa

. CC-BY-NC-ND 4.0 International license is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/724716 doi: bioRxiv preprint The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/724716 doi: bioRxiv preprint The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/724716 doi: bioRxiv preprint is targeted to the plasma membrane via an unknown mechanism. It is retrieved from the plasma membrane (purple) and transported to the TGN (light purple). AP2M is not directly involved in this process. From the TGN, the MP is recycled back to the plasma membrane (orange). The Y motif (gray box) possibly acts as a structural motif rather than a functional internalization motif, whereas the LL motif (pink box) is required for correct plasmodesmal targeting of MP. TGN/EE, trans-Golgi network/ early endosome; PM, plasma membrane; PD, plasmodesmata. The model was created with BioRender.com . CC-BY-NC-ND 4.0 International license is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/724716 doi: bioRxiv preprint OuMV-MP_Y 0/6 0/6 0/6 0/12 0/12 0/12