Author: Strating, Jeroen R.P.; van der Schaar, Hilde M.; van Kuppeveld, Frank J.M.
Title: Cholesterol: fa(s)t-food for enterovirus genome replication Cord-id: 8gd73q0h Document date: 2013_10_6
ID: 8gd73q0h
Snippet: Hijacking and remodeling of host membranes is an obligatory step in the replicative cycle of (+)RNA viruses, including enteroviruses. Ilnytska et al. unveiled in Cell Host & Microbe that enteroviruses usurp clathrin-mediated endocytosis to shuttle cholesterol to sites of genome replication and that cholesterol is needed for efficient replication.
Document: Hijacking and remodeling of host membranes is an obligatory step in the replicative cycle of (+)RNA viruses, including enteroviruses. Ilnytska et al. unveiled in Cell Host & Microbe that enteroviruses usurp clathrin-mediated endocytosis to shuttle cholesterol to sites of genome replication and that cholesterol is needed for efficient replication.
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