Evaluation of the disease outcome in Covid-19 infected patients by disease symptoms: a retrospective cross-sectional study in Ilam Province, Iran

Sadeghifar, Jamil; Jalilian, Habib; Momeni, Khalil; Delam, Hamed; Sheleme, Tadesse; Rashidi, Ayoub; Hemmati, Fariba; Falahi, Shahab; Arab-Zozani, Morteza

Backgroundnovel coronavirus disease-19 (COVID-19) announced as a global pandemic in the year 2020. With the spread of the disease, a better understanding of patient outcomes associated with their symptoms in diverse geographic levels is vital. We aimed to analysis clinical outcomes of COVID-19 patients by disease symptoms in Ilam province of Iran. MethodsThis is a retrospective study. Data were collected from integrated health system records for all hospitals affiliated to Ilam University of Medical Sciences between 26 Jan 2020 and 02 May 2020. All patients with definite positive test were enrolled in this study. We used descriptive analyses, chi-square test and binary logistic regression to analyze the data using SPSS version 22. ResultsThe mean age was 46.47{+/-}18.24 years. Of 3608 patients, 3477 (96.1%) were discharged and 129 (3.9%) were died. 54.2% of the patients were male and were in the age group of 30-40 years old age. Cough, sore throat, shortness of breath or difficulty breathing and fever or chills were the most common symptoms. People with symptoms of shortness of breath, abnormal radiographic findings of the chest, and chest pain and pressure were relatively more likely to die. Based on the findings of binary logistic regression probability of death in people who showed shortness of breath, abnormal chest radiographic findings and chest pain was 1.34, 1.24 and 1.32 times higher than those who did not show these symptoms, respectively. ConclusionOur study provides evidence that presentation of some symptoms does significantly impact on outcomes of patients infected with SARS-CoV-2. Early detection of symptoms and proper management of outcomes can reduce mortality in patients with COVID-19.