Impact of the COVID-19 pandemic on the homeless: results from a retrospective closed cohort in France (March-May 2020)

HUSAIN, Maya; RACHLINE, Anne; COUSIEN, Anthony; ROLLAND, Simon; ROUZAUD, Claire; Marie FERRE, Valentine; GOMEZ, Maria VARGAS.; TEURNIER, Maï LE.; WICKY-THISSE, Marie; DESCAMPS, Diane; YAZDANPANAH, Yazdan; CHARPENTIER, Charlotte; PASQUET-CADRE, Armelle

OBJECTIVES: To evaluate SARS-CoV-2 infection attack, hospitalization and fatality rates in residents of homeless shelters run by Samusocial of Paris. METHODS: We conducted a retrospective serological study on all residents and staff members of three homeless shelters run by Samusocial of Paris, between July and August 2020: 2 centres providing healthcare accommodation (HCA) and one women’s dormitory. We included all adults present in the shelters or who died of a proven SARS-CoV-2 infection during the first wave (March-May). SARS-CoV-2 antibodies were detected in serum samples using the SARS-CoV-2 IgG Architect (Abbott) test. Any participant with a positive PCR or serology was defined as a confirmed SARS-CoV-2 case. RESULTS: We included 100 residents and 83 staff members. The confirmed SARS-CoV-2 rate by PCR or serology was 72/100 (72.0%) for residents and 17/83 (20.5%) for staff members. Women accommodated in the dormitory had the highest infection attack rate (90.6%). Hospitalization rate in residents was 17/72 (23.6%) and the death rate 4/72 (5.6%). All hospitalizations and deaths occurred among HCA residents. 34/68 (50%) of the residents of HCA shelters presented at least two comorbidity factors associated with being at high risk for severe SARS-CoV-2 infection. CONCLUSION: SARS-CoV-2 infection rate was high in residents of these homeless shelters (10.6% seroprevalence in the Île-de-France region during the first wave). Severe SARS-CoV-2 infection was highly associated with the prevalence of comorbidities. This population should be considered as a priority in vaccination campaigns and in access to individual housing units when at risk.