Author: Xiaoyang Ji; Chunming Zhang; Yubo Zhai; Zhonghai Zhang; Yiqing Xue; Chunli Zhang; Guangming Tan; Gang Niu
Title: TWIRLS, an automated topic-wise inference method based on massive literature, suggests a possible mechanism via ACE2 for the pathological changes in the human host after coronavirus infection Document date: 2020_2_26
ID: f21dknmb_26
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.02. 24.20025437 doi: medRxiv preprint CSHGs in these networks were associated with C3 or C10 categories, and five genes (CCL3, CCL5, CXCL1, CXCL2, and STAT2) were associated with both. This suggests that the biological mechanisms described by the C3 and C10 categories might be universally involved. Research on the entities, genes, pathways, and .....
Document: The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.02. 24.20025437 doi: medRxiv preprint CSHGs in these networks were associated with C3 or C10 categories, and five genes (CCL3, CCL5, CXCL1, CXCL2, and STAT2) were associated with both. This suggests that the biological mechanisms described by the C3 and C10 categories might be universally involved. Research on the entities, genes, pathways, and linker genes participating in the C3 and C10 categories could lead to new directions for the prevention, treatment, and clinical management of coronavirus infections.
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