Selected article for: "early warning system and pathogen outbreak"

Author: Mark Hernandez; Lauren E Milechin; Shakti K Davis; Rich DeLaura; Kajal T Claypool; Albert Swiston
Title: The Impact of Host-Based Early Warning on Disease Outbreaks
  • Document date: 2020_3_8
  • ID: 8874c8jp_2
    Snippet: We have developed a series of epidemiological models that quantify the potential impact of a host-based early warning capability to mitigate pathogen transmission during an outbreak. Our epidemiological models reflect a variety of traditional public health policies related to nonpharmaceutical interventions, such as quarantine and patient isolation, and novel policies enabled by host-based early warning capabilities, such as the PRESAGED system [.....
    Document: We have developed a series of epidemiological models that quantify the potential impact of a host-based early warning capability to mitigate pathogen transmission during an outbreak. Our epidemiological models reflect a variety of traditional public health policies related to nonpharmaceutical interventions, such as quarantine and patient isolation, and novel policies enabled by host-based early warning capabilities, such as the PRESAGED system [1] . For each policy-dependent model, we simulated outbreak scenarios and calculated the size of the outbreak (total number of infections) and the operational burden (total number of lost duty days resulting from quarantine or isolation). These metrics were used to understand the trade space for the different policies. Our simulations demonstrate the utility of host-based early warning systems in controlling an outbreak under various outbreak conditions.

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