Author: Keitel, Verena; Bode, Johannes Georg; Feldt, Torsten; Walker, Andreas; Müller, Lisa; Kunstein, Anselm; Klindt, Caroline; Killer, Alexander; Senff, Tina; Timm, Jörg; Ostermann, Philipp; Damagnez, Maximilian; Lübke, Nadine; Adams, Ortwin; Schaal, Heiner; Antoch, Gerald; Neubert, Jennifer; Albrecht, Philipp; Meuth, Sven; Elben, Saskia; Mohring, Annemarie; Fischer, Johannes C.; Bölke, Edwin; Hoenig, Manfred; Schulz, Ansgar S.; Luedde, Tom; Jensen, Björn
Title: Case Report: Convalescent Plasma Achieves SARS-CoV-2 Viral Clearance in a Patient With Persistently High Viral Replication Over 8 Weeks Due to Severe Combined Immunodeficiency (SCID) and Graft Failure Cord-id: 8fsijm8i Document date: 2021_5_3
ID: 8fsijm8i
Snippet: We describe the unique disease course and cure of SARS-CoV-2 infection in a patient with SCID and graft failure. In absence of a humoral immune response, viral clearance was only achieved after transfusion of convalescent plasma. This observation underscores the necessity of the humoral immune response for SARS-CoV-2 clearance.
Document: We describe the unique disease course and cure of SARS-CoV-2 infection in a patient with SCID and graft failure. In absence of a humoral immune response, viral clearance was only achieved after transfusion of convalescent plasma. This observation underscores the necessity of the humoral immune response for SARS-CoV-2 clearance.
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