Author: Jason W. Westerbeck; Carolyn E. Machamer
Title: The Infectious Bronchitis Virus Coronavirus Envelope Protein Alters Golgi pH to Protect Spike Protein and Promote Release of Infectious Virus Document date: 2018_10_11
ID: amg5dice_18
Snippet: What is striking about IBV E when compared to M2 or p7 is the notion that IBV E is likely causing secretory pathway disruption in an IBV E ion-channel independent way. If IBV E is acting as a monomer to elicit secretory pathway disruption and alter pH, interaction of IBV E with a host protein(s) or lipid(s) would be necessary......
Document: What is striking about IBV E when compared to M2 or p7 is the notion that IBV E is likely causing secretory pathway disruption in an IBV E ion-channel independent way. If IBV E is acting as a monomer to elicit secretory pathway disruption and alter pH, interaction of IBV E with a host protein(s) or lipid(s) would be necessary.
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