Author: Shen, Jun; Sun, Jing; Zhao, Danyang; Li, Suyun; Xiao, Weiqiang; Cai, Xian; Yan, Jianjiang; Zhu, Weidong; Guo, Qiaozhi; Wen, Xiulan; Wu, Jinxia; Shi, Xuan; Jiang, Daoju; Huang, Jing; Luo, Jiaming; Chen, Huan; Hong, Yan; Ma, Wencheng; Liu, Guangming; Yang, Haomei; Wang, Qiang; Song, Yongling; Lin, Jinai; Sun, Xin; Li, Peiqing
Title: Characteristics of Nosocomial Infections in Children Screened for SARS-CoV-2 Infection in China Cord-id: h14hi4rk Document date: 2020_12_18
ID: h14hi4rk
Snippet: BACKGROUND: This study summarizes the characteristics of children screened for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and reports the case of 1 child who was diagnosed with SARS-CoV-2 infection in Guangzhou Women and Children’s Medical Center and the cases of his family members. MATERIAL/METHODS: The medical records of 159 children who were admitted to our hospital from January 23 to March 20, 2020, were retrospectively analyzed. Samples from pharyngeal or/and a
Document: BACKGROUND: This study summarizes the characteristics of children screened for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and reports the case of 1 child who was diagnosed with SARS-CoV-2 infection in Guangzhou Women and Children’s Medical Center and the cases of his family members. MATERIAL/METHODS: The medical records of 159 children who were admitted to our hospital from January 23 to March 20, 2020, were retrospectively analyzed. Samples from pharyngeal or/and anal swabs were subjected to reverse-transcription polymerase chain reaction (RT-PCR) testing for SARS-CoV-2 within 12 h of patient admission; a second RT-PCR test was done 24 h after the first test. RESULTS: Of the 159 patients, 151 patients had epidemiological histories, 14 patients had cluster onset, and 8 patients had no epidemiological history but had symptoms similar to coronavirus disease 2019 (COVID-19). The most common symptom was fever (n=125), followed by respiratory and gastrointestinal symptoms. A 7-year-old boy in a cluster family from Wuhan was confirmed with asymptomatic SARS-CoV-2 infection with ground-glass opacity shadows on his lung computed tomography scan, and his swab RT-PCR test had not turned negative until day 19 of his hospitalization. In patients who did not test positive for SARS-CoV-2, influenza, respiratory syncytial virus, and adenovirus were observed. A total of 158 patients recovered, were discharged, and experienced no abnormalities during follow-up. CONCLUSIONS: For SARS-CoV-2 nosocomial infections, taking a “standard prevention & contact isolation & droplet isolation & air isolation†strategy can prevent infection effectively. Children with clustered disease need close monitoring.
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