Author: Linlin Zhang; Daizong Lin; Yuri Kusov; Yong Nian; Qingjun Ma; Jiang Wang; Albrecht von Brunn; Pieter Leyssen; Kristina Lanko; Johan Neyts; Adriaan de Wilde; Eric J. Snijder; Hong Liu; Rolf Hilgenfeld
Title: Alpha-ketoamides as broad-spectrum inhibitors of coronavirus and enterovirus replication Document date: 2020_2_10
ID: 7n8p9okf_75
Snippet: Compound 2 (1.0 g, 3.5 mmol) was dissolved in 10 mL dichloromethane (DCM), then 10 mL trifluoroacetic acid (TFA) was added. The reaction mixture was stirred at 20 o C for 0.5 h, and concentrated in vacuo to get a colorless oil, which could be used for the following step without purification......
Document: Compound 2 (1.0 g, 3.5 mmol) was dissolved in 10 mL dichloromethane (DCM), then 10 mL trifluoroacetic acid (TFA) was added. The reaction mixture was stirred at 20 o C for 0.5 h, and concentrated in vacuo to get a colorless oil, which could be used for the following step without purification.
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