Selected article for: "discontinuous RNA synthesis and RNA strand pair"

Author: Hazel Stewart; Katherine Brown; Adam M. Dinan; Nerea Irigoyen; Eric J. Snijder; Andrew E. Firth
Title: The transcriptional and translational landscape of equine torovirus
  • Document date: 2018_4_7
  • ID: mozfm5ds_41
    Snippet: This leads to the suggestion that homology between any two sites may be sufficient 392 to induce discontinuous RNA synthesis, i.e. that provided adequate sequence 393 homology exists, the nascent RNA strand may re-pair with upstream sites within the 394 genomic RNA regardless of the presence of a predefined TRS. This is consistent with 395 the 5' UTR-ORF1b chimaeric transcripts, which again revealed a particular sequence 396 that could be templat.....
    Document: This leads to the suggestion that homology between any two sites may be sufficient 392 to induce discontinuous RNA synthesis, i.e. that provided adequate sequence 393 homology exists, the nascent RNA strand may re-pair with upstream sites within the 394 genomic RNA regardless of the presence of a predefined TRS. This is consistent with 395 the 5' UTR-ORF1b chimaeric transcripts, which again revealed a particular sequence 396 that could be templated from either region, in this case AACCUUA rather than the 397

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