Selected article for: "different type and emergency department"
Author: Halil Özdemir, İbrahim; Özlek, Bülent; Burak Özen, Mehmet; Gündüz, Ramazan; Bayturan, Özgür
Title: Type 1 Kounis syndrome induced by inactivated SARS-CoV-2 vaccine
  • Cord-id: 8pad9j4c
  • Document date: 2021_5_7
    • ID: 8pad9j4c
    Snippet: BACKGROUND: : Vaccination is the most important way to out of the novel coronavirus disease (COVID-19). Vaccination practices have started in different countries for community immunity. In this process, health authorities in different countries have preferred different type of COVID-19 vaccines. Inactivated COVID-19 vaccine is one of these options and has been administered to more than 7 million people in Turkey. Inactivated vaccines are generally considered safe. Kounis syndrome (KS) is a rare
    Document: BACKGROUND: : Vaccination is the most important way to out of the novel coronavirus disease (COVID-19). Vaccination practices have started in different countries for community immunity. In this process, health authorities in different countries have preferred different type of COVID-19 vaccines. Inactivated COVID-19 vaccine is one of these options and has been administered to more than 7 million people in Turkey. Inactivated vaccines are generally considered safe. Kounis syndrome (KS) is a rare clinical condition which defined as the co-existence of acute coronary syndromes and allergic reactions. CASE REPORT: : We present the case of a 41-year-old female who with no cardiovascular risk factors admitted at our emergency department with flushing, palpitation, dyspnea and chest pain 15 minutes after the first dose of inactivated coronavirus vaccine (CoronaVac). Electrocardiogram (ECG) showed V4-6 T wave inversion, and echocardiography revealed left ventricular wall motion abnormalities. Troponin-I level on arrival was elevated. Coronary angiography showed no sign of coronary atherosclerosis. She was diagnosed with type 1 KS. The patient's symptoms resolved and she discharged from hospital in a good condition. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS? : To the best of our knowledge, this is the first case of allergic myocardial infarction secondary to inactivated coronavirus vaccine. This case demonstrates that KS may occur after inactivated virus vaccine against COVID-19. Although the risk of severe allergic reaction after CoronaVac administration seems to be very low, persons who developed chest pain after vaccine administration should be followed by ECG and troponin measurements.

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