Author: Cowling, Benjamin J.; Chan, Kwok-Hung; Feng, Shuo; Chan, Eunice L.Y.; Lo, Janice Y.C.; Peiris, J. S. Malik; Chiu, Susan S.
Title: The effectiveness of influenza vaccination in preventing hospitalizations in children in Hong Kong, 2009–2013 Cord-id: 98v5kmus Document date: 2014_9_15
ID: 98v5kmus
Snippet: Abstract Background Influenza vaccination is widely recommended every year to protect individuals against influenza virus infection and illness. There are few published estimates of influenza vaccine effectiveness against hospitalization in children or from subtropical regions. Methods We conducted a test-negative year-round study between October 2009 and September 2013, recruiting children 6months to 17years of age admitted to two hospitals in Hong Kong with a febrile acute respiratory infectio
Document: Abstract Background Influenza vaccination is widely recommended every year to protect individuals against influenza virus infection and illness. There are few published estimates of influenza vaccine effectiveness against hospitalization in children or from subtropical regions. Methods We conducted a test-negative year-round study between October 2009 and September 2013, recruiting children 6months to 17years of age admitted to two hospitals in Hong Kong with a febrile acute respiratory infection. Cases were tested for influenza A and B and conditional logistic regression was used to estimate vaccine effectiveness comparing influenza vaccination history of the trivalent influenza vaccine (TIV) among patients testing positive versus negative for influenza, adjusting for age and sex and matching by calendar week of recruitment. Results Overall vaccine effectiveness against hospitalization with laboratory-confirmed influenza A and B was estimated to be 61.7% (95% CI: 43.0%, 74.2%). The estimated vaccine effectiveness against A(H3N2) was 36.6% (95% CI: −25.5%, 67.9%) compared to 71.5% (95% CI: 39.4%, 86.6%) for A(H1N1)pdm09 and 68.8% (95% CI: 41.6%, 83.3%) for B. Conclusions Vaccine effectiveness against hospitalization in children varied from year to year, but was moderate to high overall even in an area with influenza activity throughout the year.
Search related documents:
Co phrase search for related documents- acute respiratory infection and admit child: 1
- acute respiratory infection and logistic regression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute respiratory infection and logistic regression model: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute respiratory infection and low immunity: 1, 2, 3
- acute respiratory infection and low uptake: 1, 2
- acute respiratory infection and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute respiratory infection case and logistic regression: 1, 2, 3
- acute respiratory infection case and logistic regression model: 1
- acute respiratory infection case and lung disease: 1
- adequate protection and logistic regression: 1, 2, 3, 4, 5
- adequate protection and logistic regression model: 1
- adequate protection and low immunity: 1
- adjusted ve and logistic regression: 1, 2, 3, 4, 5, 6, 7, 8
- admit child and lung disease: 1
- logistic regression and low immunity: 1, 2, 3
- logistic regression and low uptake: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21
- logistic regression and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- logistic regression model and low uptake: 1, 2
- logistic regression model and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
Co phrase search for related documents, hyperlinks ordered by date