Author: Fragoso, Yara D; Gomes, Sidney; Gonçalves, Marcus Vinicius M; Junior, Euldes Mendes; de Oliveira, Bianca Etelvina S; Rocha, Cristiane Franklin; Cruz dos Santos, Gutemberg A; Tauil, Carlos Bernardo; Araujo, Raquel Vassao; Peron, Jean Pierre S
Title: New relapse of multiple sclerosis and neuromyelitis optica as a potential adverse event of AstraZeneca AZD1222 vaccination for COVID-19 Cord-id: 4f40ctvu Document date: 2021_10_13
ID: 4f40ctvu
Snippet: We report on nine patients (eight cases of MS and one case of NMOSD) who presented a disease relapse in close temporal association with their first AZD1222 vaccination dose against COVID-19. These patients had been stable for a median period of six years, with no evidence of disease activity and no change in their medication. After a median of 13 days (7 to 25 days) from vaccination, they developed a new relapse with increased disability and new lesions on magnetic resonance imaging. Although ex
Document: We report on nine patients (eight cases of MS and one case of NMOSD) who presented a disease relapse in close temporal association with their first AZD1222 vaccination dose against COVID-19. These patients had been stable for a median period of six years, with no evidence of disease activity and no change in their medication. After a median of 13 days (7 to 25 days) from vaccination, they developed a new relapse with increased disability and new lesions on magnetic resonance imaging. Although exceedingly rare, this might be an adverse event of AZD1222.
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