Vaccine design and delivery approaches for COVID-19

Shahzamani, Kiana; Mahmoudian, Fatemeh; Ahangarzadeh, Shahrzad; Ranjbar, Mohammad Mehdi; Beikmohammadi, Leila; Bahrami, Samira; Mohammadi, Elmira; Esfandyari, Sahar; Alibakhshi, Abbas; Javanmard, Shaghayegh Haghjooy

COVID-19 is still a deadly disease that remains yet a major challenge for humans. In recent times, many large pharmaceutical and non-pharmaceutical companies have invested a lot of time and cost in fighting this disease. In this regard, today's scientific knowledge shows that designing and producing an effective vaccine is the best possible way to diminish the disease burden and dissemination or even eradicate the disease. Due to the urgent need, many vaccines are now available earlier than scheduled. New technologies have also helped to produce much more effective vaccines, although the potential side effects must be taken into account. Thus, in this review, the types of vaccines and vaccine designs made against COVID-19, the vaccination programs, as well as the delivery methods and molecules that have been used to deliver some vaccines that need a carrier will be described.