Selected article for: "diffuse alveolar damage and extensive damage"

Author: Mukhopadhyay, Sanjay; Philip, Abraham T.; Stoppacher, Robert
Title: Pathologic Findings in Novel Influenza A (H1N1) Virus (“Swine Flu”) Infection: Contrasting Clinical Manifestations and Lung Pathology in Two Fatal Cases
  • Cord-id: 8swdf9zy
  • Document date: 2010_3_1
  • ID: 8swdf9zy
    Snippet: Although novel influenza A (H1N1) virus infection has assumed pandemic proportions, there are few reports of the pathologic findings. Herein we describe the pathologic findings of novel influenza A (H1N1) infection based on findings in 2 autopsy cases. The first patient, a 36-year-old man, had flu-like symptoms; oseltamivir (Tamiflu) therapy was started 8 days after onset of symptoms, and he died on day 15 of his illness. At autopsy, the main finding was diffuse alveolar damage with extensive fr
    Document: Although novel influenza A (H1N1) virus infection has assumed pandemic proportions, there are few reports of the pathologic findings. Herein we describe the pathologic findings of novel influenza A (H1N1) infection based on findings in 2 autopsy cases. The first patient, a 36-year-old man, had flu-like symptoms; oseltamivir (Tamiflu) therapy was started 8 days after onset of symptoms, and he died on day 15 of his illness. At autopsy, the main finding was diffuse alveolar damage with extensive fresh intra-alveolar hemorrhage. The second patient, a 46-year-old woman with alcoholism, was found unresponsive in a basement and brought to the hospital intoxicated and confused. Her condition deteriorated rapidly, and she died 4 days after admission. The main autopsy finding was acute bronchopneumonia with gram-positive cocci, intermixed with diffuse alveolar damage. The pathologic findings in these contrasting cases of novel influenza A (H1N1) infection are similar to those previously described for seasonal influenza. The main pathologic abnormality in fatal cases is diffuse alveolar damage, but it may be overshadowed by an acute bacterial bronchopneumonia.

    Search related documents:
    Co phrase search for related documents
    • acute bronchopneumonia and lung tissue: 1, 2, 3
    • acute important and lung tissue: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • acute inflammation and lung parenchyma: 1, 2, 3, 4, 5
    • acute inflammation and lung tissue: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23
    • acute pneumonia and lung parenchyma: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • acute pneumonia and lung sample: 1
    • acute pneumonia and lung tissue: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • acute stage and lung parenchyma: 1
    • acute stage and lung tissue: 1, 2, 3, 4
    • acute stage diffuse dad alveolar damage and lung tissue: 1
    • liver weight and lung tissue: 1
    • local laboratory and lung tissue: 1
    • low magnification and lung tissue: 1