Author: Chuang Liu; Yang Yang; Yuanzhu Gao; Chenguang Shen; Bin Ju; Congcong Liu; Xian Tang; Jinli Wei; Xiaomin Ma; Weilong Liu; Shuman Xu; Yingxia Liu; Jing Yuan; Jing Wu; Zheng Liu; Zheng Zhang; Peiyi Wang; Lei Liu
Title: Viral Architecture of SARS-CoV-2 with Post-Fusion Spike Revealed by Cryo-EM Document date: 2020_3_5
ID: cr22vp8b_12
Snippet: For majority of the virions, the periphery is well defined and enveloped by lipid bilayer, which could be clearly seen in cryo-EM image. Tightly underneath the lipid bilayer is the condensed density formed by nucleic acid and nucleocapsid protein of SARS-CoV-2. Though lots of the particles lost spike during purification or deactivation, 20%-30% percent virions still have spikes around the envelope......
Document: For majority of the virions, the periphery is well defined and enveloped by lipid bilayer, which could be clearly seen in cryo-EM image. Tightly underneath the lipid bilayer is the condensed density formed by nucleic acid and nucleocapsid protein of SARS-CoV-2. Though lots of the particles lost spike during purification or deactivation, 20%-30% percent virions still have spikes around the envelope.
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