Selected article for: "class ii and MHC class"
Author: A.J.W. Haasnoot; M.W. Schilham; S.S.M. Kamphuis; P.C.E. Hissink Muller; A. Heiligenhaus; D. Foell; R.A. Ophoff; T.R.D.J. Radstake; A.I. Den Hollander; T.H.C.M. Reinards; S. Hiddingh; N. Schalij-Delfos; E.P.A.H. Hoppenreijs; M.A.J. van Rossum; C. Wouters; R.K. Saurenmann; N. Wulffraat; R. ten Cate; J.H. de Boer; S.L. Pulit; J.J.W. Kuiper
Title: An amino acid motif in HLA-DRß1 distinguishes patients with uveitis in juvenile idiopathic arthritis
  • Document date: 2017_5_22
    • ID: 4it5c9n2_50
    Snippet: To impute amino acids and HLA alleles in the MHC, we used the SNP2HLA pipeline. 29 In short, the SNP2HLA pipeline uses a reference panel assembled through HLA typing of 5,225 European-ancestry individuals collected by the Type 1 Diabetes Genetics Consortium. 77 The panel includes SNPs and amino acids in the MHC, as well as HLA types from the Class I (HLA-A, HLA-B, and HLA-C) and Class II (HLA-DRB1, HLA-DQA1, HLA-DQB1, HLA-DPA1, and HLA-DPB1) HLA .....
    Document: To impute amino acids and HLA alleles in the MHC, we used the SNP2HLA pipeline. 29 In short, the SNP2HLA pipeline uses a reference panel assembled through HLA typing of 5,225 European-ancestry individuals collected by the Type 1 Diabetes Genetics Consortium. 77 The panel includes SNPs and amino acids in the MHC, as well as HLA types from the Class I (HLA-A, HLA-B, and HLA-C) and Class II (HLA-DRB1, HLA-DQA1, HLA-DQB1, HLA-DPA1, and HLA-DPB1) HLA genes. HLA types are imputed to 2-and 4-digit resolution. The SNP2HLA pipeline uses BEAGLE 78 to phase the data and then impute.

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