Author: Amrita Roy; Liangzhong Lim; Shagun Srivastava; Jianxing Song
Title: Unique properties of Zika NS2B-NS3pro complexes as decoded by experiments and MD simulations Document date: 2016_9_28
ID: l82aakrk_36
Snippet: However, despite being less disordered, this complex showed no detectable enzymatic activity even with the protease concentration up to 20 µM, suggesting that this complex is completely inactive. Previously, we have generated a truncated Dengue NS2B with the C-terminal residues deleted but the short NS2B lost the capacity in forming a soluble complex with its NS3pro......
Document: However, despite being less disordered, this complex showed no detectable enzymatic activity even with the protease concentration up to 20 µM, suggesting that this complex is completely inactive. Previously, we have generated a truncated Dengue NS2B with the C-terminal residues deleted but the short NS2B lost the capacity in forming a soluble complex with its NS3pro.
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