MO606 FUNCTIONAL CAPACITY AND NUTRITION-INFLAMMATION BINOMIUM IN PATIENTS WITH ADVANCED CHRONIC KIDNEY DISEASE (ACKD)

Nogueira, Ángel; Alvarez, Graciela; Barril, Guillermina

BACKGROUND AND AIMS: There are differents factors that will influence the functional capacity of ACKD patients, among them the nutritional condition. AIM: to assess the functional capacity of ACKD patients with the Short Physical Performance test Battery (SPPB), and its relationship with the malnutrition-inflammation binomium. METHOD: We have evaluated 216 ACKD patients, 66.2% (143) male. xage 70.85 ?12.01 years, being female older than male (72.58 ?13.19 vs 69.96 ?11.32, p = 0.129). We have determine plasma proteins indicators of nutritional status such as albumin, prealbumin and CRP as a marker of the status of inflammation. And we have applied malnutrition inflamation score (MIS). RESULTS: In the univariate analysis, we found an association between the functionality determined with the test and the age (RR95% 0.866 p = 0.000), sex (RR95% 0.387 p = 0.005). albumin (RR95% 2,222 p = 0.035), prealbumin (RR95% 1.065 p = 0.018), CRP (RR95% 0.733 p = 0.022) and the state nutritional value determined with the MIS scale (RR95% 0.791 p = 0.000). We donot any found any association with DM, transferrin and total lymphocytes. Albumin values were established as 3.8g / dl, and CRP at 1g / dl, obtaining 4 groups: (G1: alb> 3,7-PCR <1, G2: alb> 3,7-PCR> 1, G3: alb <3,7-PCR <1 and G4: alb <3,7-PCR> 1 ). The table shows the results of the relationship between groups and the limitations determined with SPBB. Group 1 was the most numerous, also being the one with the best nutrition-inflammation profile, observing that in this group 68 patients (78.2%) presented minimal / no limitations. CONCLUSIONS: 1. The nutritional-inflammation status will influence the functional capacity of the patient with ERCA. 2. The SPPB test, in addition to being a good choice to evaluate the functional capacity of patients with ACKD, can provide guidance on the nutritional status of patients. 3. Maintaining a good nutritional status will also have a positive influence on the functional capacity of ACKD patients.