Author: Sha Fu; Xiaoyu Fu; Yang Song; Min Li; Pin-hua Pan; Tao Tang; Chunhu Zhang; Tiejian Jiang; Deming Tan; Xuegong Fan; Xinping Sha; Jingdong Ma; Yan Huang; Shaling Li; Yixiang Zheng; Zhaoxin Qian; Zeng Xiong; Lizhi Xiao; Huibao Long; Jianghai Chen; Yi Ouyang
Title: Virologic and clinical characteristics for prognosis of severe COVID-19: a retrospective observational study in Wuhan, China Document date: 2020_4_6
ID: 4989atst_15
Snippet: In addition, the serologic tests for SARS-Cov-2 also differed greatly between the two groups. The presence of prolonged SARS-CoV-2 IgM was closely associated with the poor recovery of patients with COVID-19 (p=0.03, Table2). A total of 11 out of 12 (91.66%) patients with good recovery have positive IgG, but negative IgM after hospitalization for one month. In contrast, 15 (51.7%, 15/29) patients with poor recovery had positive test results for bo.....
Document: In addition, the serologic tests for SARS-Cov-2 also differed greatly between the two groups. The presence of prolonged SARS-CoV-2 IgM was closely associated with the poor recovery of patients with COVID-19 (p=0.03, Table2). A total of 11 out of 12 (91.66%) patients with good recovery have positive IgG, but negative IgM after hospitalization for one month. In contrast, 15 (51.7%, 15/29) patients with poor recovery had positive test results for both IgM and IgG. As of March 17, 2020, the longest duration of IgM was 55 days at onset of illness, indicating that severe patients with poor recovery were more likely to have a prolonged acute phase of the illness.
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