Selected article for: "consequence cause and disease consequence cause"
Author: Narayan, Bhaskar; Nelson-Piercy, Cathy
Title: Physiological Changes of the Immune System During Pregnancy
  • Cord-id: dh1uiin1
  • Document date: 2020_5_12
    • ID: dh1uiin1
    Snippet: Pregnancy is a unique immunological state, during which there are pro-inflammatory changes as well as increased immune tolerance. A shift occurs from a Th1- towards a Th2-predominant immunological profile. As a consequence, certain infections cause more severe disease in pregnancy. The immunological changes also influence the activity of autoimmune diseases, which are relatively common in pregnant women and may require critical care admission. Identifying autoimmune flares may be more challengin
    Document: Pregnancy is a unique immunological state, during which there are pro-inflammatory changes as well as increased immune tolerance. A shift occurs from a Th1- towards a Th2-predominant immunological profile. As a consequence, certain infections cause more severe disease in pregnancy. The immunological changes also influence the activity of autoimmune diseases, which are relatively common in pregnant women and may require critical care admission. Identifying autoimmune flares may be more challenging during pregnancy, as some features may overlap with normal pregnancy and/or pre-eclampsia. Many immunosuppressive treatments can be used during pregnancy and should not be withheld if clinically indicated.

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