Author: Jing-Wen Ai; Hao-Cheng Zhang; Teng Xu; Jing Wu; Mengqi Zhu; Yi-Qi Yu; Han-Yue Zhang; Zhongliang Shen; Yang Li; Xian Zhou; Guo-Qing Zang; Jie Xu; Wen-Jing Chen; Yong-Jun Li; De-Sheng Xie; Ming-Zhe Zhou; Jing-Ying Sun; Jia-Zhen Chen; Wen-Hong Zhang
Title: Optimizing diagnostic strategy for novel coronavirus pneumonia, a multi-center study in Eastern China Document date: 2020_2_17
ID: nqxo3f45_20
Snippet: In our study, we enrolled 53 suspected cases and 20 cases were finally laboratory-confirmed with NCP, among which 11 patients were also co-infected with other pathogens. Other causative pathogens were detected through multiplex respiratory PCR panel and mNGS, and in the non-NCP groups, some pathogens, such as RSV, parainfluenza virus may share very similar radiological patterns as the NCP group, including bilateral multiple lobular, groundglass o.....
Document: In our study, we enrolled 53 suspected cases and 20 cases were finally laboratory-confirmed with NCP, among which 11 patients were also co-infected with other pathogens. Other causative pathogens were detected through multiplex respiratory PCR panel and mNGS, and in the non-NCP groups, some pathogens, such as RSV, parainfluenza virus may share very similar radiological patterns as the NCP group, including bilateral multiple lobular, groundglass opacity, and consolidation. This indicated that for regions in Eastern China, pathogens other than SARS-COV-2 still composed of approximately 60% of the suspected unexplained pneumonia; therefore, chest CT alone could not be used as a diagnostic criterion for SARS-COV-2 infections. A combination of chest CT and other diagnostic methods is essential to decrease the chance of misdiagnosis in areas outside Hubei Province.
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