Author: A.J.W. Haasnoot; M.W. Schilham; S.S.M. Kamphuis; P.C.E. Hissink Muller; A. Heiligenhaus; D. Foell; R.A. Ophoff; T.R.D.J. Radstake; A.I. Den Hollander; T.H.C.M. Reinards; S. Hiddingh; N. Schalij-Delfos; E.P.A.H. Hoppenreijs; M.A.J. van Rossum; C. Wouters; R.K. Saurenmann; N. Wulffraat; R. ten Cate; J.H. de Boer; S.L. Pulit; J.J.W. Kuiper
Title: An amino acid motif in HLA-DRß1 distinguishes patients with uveitis in juvenile idiopathic arthritis Document date: 2017_5_22
ID: 4it5c9n2_5
Snippet: In Phase 2, an additional 77 JIA-associated uveitis cases and 115 JIA without uveitis samples (total N = 192), collected from Germany, Belgium and Switzerland, were genotyped on the same array. Samples and SNPs underwent QC nearly identical to that of Phase 1 (Materials and Methods). After QC, 66 JIA-associated uveitis cases and 99 nonuveitis JIA samples remained for analysis. The cleaned genotyping data was prephased and imputed both genome-wide.....
Document: In Phase 2, an additional 77 JIA-associated uveitis cases and 115 JIA without uveitis samples (total N = 192), collected from Germany, Belgium and Switzerland, were genotyped on the same array. Samples and SNPs underwent QC nearly identical to that of Phase 1 (Materials and Methods). After QC, 66 JIA-associated uveitis cases and 99 nonuveitis JIA samples remained for analysis. The cleaned genotyping data was prephased and imputed both genome-wide and within the MHC, precisely as in Phase 1.
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